Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
We are working against the grain of the wood A woodworker works along the grain of the wood to prevent splinter. A butcher slices across to the muscle fiber to improve tenderness. A sailor trims the sail to balance the lift and drag from the wind. When we respect the material, the material pays us back in convenience, safety, and efficiency. Good web design requires the same understanding of and respect for the materials. And that material is the browser, along with its semantic HTML, default styles, and standard behaviors. But the wide use of design software such as Figma, Sketch, and AdobeXD has trivialized the nuances of such material into “canvases” or “artboards” of pre-defined sizes. The convenient styling and manipulation of pixels and objects have disguised the hierarchy of the DOM, the constraints of the device, and the personal preferences and browser setting from real users. Dishonest tools encourage dishonest design. We are working against the grain of the wood. Chuánqí Sun, A case against "pixel perfect" design The Web's GrainWhat the brick really wants.What the material wants to be materialwwwdesign