Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Unfolding In short, the architect is responsible for building construction, is watching the building unfold continuously, and is making ongoing modifications as it becomes clear from each given stage, what modifications and changes should be made at each moment. And this is all to be done within a management framework that controls budget and cost very tightly. Christopher Alexander, The Battle for the Life and Beauty of the Earth In terms which must be altered