Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
The situation talks back As the designer shapes the situation in accordance with his initial presentation of it, the situation “talks back” and he responds to the situation’s back-talk. In a good process of design, this conversation with the situation is reflexive. In answer to the situation’s back-talk, the designer reflects-in-action on the construction of the problem, the strategies of action, or the model of the phenomena, which have been implicit in his moves. What's wrong with the rational modelWhat the prototype tells youExpressing ideas helps to form themThe idea grows as they workDrawing as a means of thinkingFour principlesWriting, Briefly design