Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Small economies I refer to small money-earning business that consist of the work of a visible individual, or have evolved from a personal hobby or skill, as "small economies". We can include in this category newer forms of at-home work—side businesses, telecommuting and the like. The amount of income is unimportant; meager profits are compensated for by the motivation of the owner. A small economy may or may not be someone's main form of livelihood, but it is always a spontaneously conceived and continuing activity. Toshiharu Naka, Two Cycles All-use environments economics