Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Sentences and words do not exist by themselves Sentences and words do not exist by themselves, but have natural, inevitable, unavoidable interactions with their surrounding spaces, words, and other sentences. Sentences are not independent of their spatial context, and interactions can create meanings and harms. Sentences survive content-indifferent and content-hostile spacings, but surviving is not thriving. Text space should not be owned and governed by generic productions grids, which make for convenient production but inconvenient meaning. Space can and should be content-responsive, actively contributing to meaning – forever practices in poetry, maps, math, computer code, comics, theater/movie scrips, posters. Subtle visual spacing differentiates and clarifies sentences, and meaning becomes more consequential, memorable, retrievable. Edward Tufte, Seeing With Fresh Eyes Concrete poetrygridless.design typography