Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Prometheus A Poem by Lord Byron www.poetryfoundation.org The lightnings trembledThe sum of human wretchednessMaking Death a Victory Subjected to some great trialA hierarchical system of senseYou find reasons to keep living deathsufferingpain
The lightnings trembled And in thy Silence was his Sentence, And in his Soul a vain repentance, And evil dread so ill dissembled, That in his hand the lightnings trembled. idefiancesilence
The sum of human wretchedness Thy Godlike crime was to be kind, To render with thy precepts less The sum of human wretchedness, And strengthen Man with his own mind; But baffled as thou wert from high, Still in thy patient energy, In the endurance, and repulse Of thine impenetrable Spirit, Which Earth and Heaven could not convulse, A mighty lesson we inherit.
Making Death a Victory Like thee, Man is in part divine, A troubled stream from a pure source; And Man in portions can foresee His own funereal destiny; His wretchedness, and his resistance, And his sad unallied existence: To which his Spirit may oppose Itself—and equal to all woes, And a firm will, and a deep sense, Which even in torture can descry Its own concenter'd recompense, Triumphant where it dares defy, And making Death a Victory. deathdestinyhumanity