Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Levels of Scale Scale refers to how we perceive the size of an element or space relative to other forms around it. All things – a tea cup, a building, language, entire eco-systems – consist of smaller components. It is the relationship of the smaller elements which determines the character and degree of life of the whole. Objects which contain a high degree of life tend to contain a beautiful range of scales within, which exist at a series of well-marked intervals and have clearly recognizable jumps between them. To have good levels of scale, it is extremely important that the jumps between different scales of centers not be too great or too small. Christopher Alexander, The Nature of Order The scale of resolution determines what is seen