Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Let the goals suggest themselves There are several ways to start the design process, depending on your nature and needs. You can start out by defining your goals, as precisely as possible, and then look at the site with these goals in mind. Or you can take the site with all its characteristics (both good and bad), and let goals suggest themselves. Of the two questions—"What can I make this land do?"—or—"What does this land have to give me?"—the first may lead to exploitation of the land without regard to long-term consequences, while the second to a sustained ecology guided by our intelligent control. Bill Mollison, Introduction to Permaculture Do not propose solutions goalsdesignsustainability