Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Designing detail My heart belongs to the details. I actually always found them to be more important than the big picture. Nothing works without details. They are everything, the baseline of quality. Truly functional design only comes from the most careful and intense attention to detail. Although he did not directly design all products and even had very little to do with some of them, he constantly encouraged tiny improvements that could make a good design better. This attention to detail ranged from the acuteness of angles in forms; the size, feels and distances between switches; the integration of handle fixings; the placement and nature of graphic elements on the products themselves and extended to product photography and packaging. Designing detail is about achieving a fine balance in all aspects and areas of the product, including those external to the object. Sophie Lovell & Dieter Rams, Dieter Rams: As Little Design as Possible The details of construction details