Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Data Farming A Research Paper onlinelibrary.wiley.com Miners seek valuable nuggets of ore buried in the earth, but have no control over what is out there or how hard it is to extract the nuggets from their surroundings. ... Similarly, data miners seek to uncover valuable nuggets of information buried within massive amounts of data. Farmers cultivate the land to maximize their yield. They manipulate the environment to their advantage using irrigation, pest control, crop rotation, fertilizer, and more. Small-scale designed experiments let them determine whether these treatments are effective. Similarly, data farmers manipulate simulation models to their advantage, using large-scale designed experimentation to grow data from their models in a manner that easily lets them extract useful information. An information service society farmingdatasimulation