Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
A state of energetic repose Read the text before designing it. Discover the outer logic of the typography in the inner logic of the text. Make the visible relationship between the text and other elements (photographs, captions, tables, diagrams, notes) a reflection of their real relationship. Give full typographic attention even to incidental details. Invite the reader into the text. Reveal the tenor and meaning of the text. Clarify the structure and the order of the text. Link the text with other existing elements. Induce a state of energetic repose, which is the ideal condition for reading. Robert Bringhurst, The Elements of Typographic Style The inner nature of material typography