Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
The work is what it means It is desirable to bear in mind—when dealing with the human maker at any rate—that his chosen way of revelation is through his works. To persist in asking, as so many of us do, “What did you mean by this book?” is to invite bafflement: the book itself is what the writer means. Dorothy Sayers, The Mind of the Maker The meaning of musicNo more than a sketchOn 'The Master and His Emissary'Only a mind opened to the quality of thingsTranslation is always a treason meaningart