Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Seven lamps Ruskin's Seven Lamps of Architecture provided seven guides, or 'lamps', for the troubled craftsman, guides for anyone who works directly on material things. These seven are: The lamp of sacrifice: The willingness to do something well for its own sake. The lamp of truth: The truth that 'breaks and rents continually'; Ruskin's embrace of difficulty, resistance, and ambiguity. The lamp of power: Tempered power, guided standards other than blind will. The lamp of beauty: Which for Ruskin is found more in the detail, the ornament—hand-sized beauty—than in the large design. The lamp of life: Life equating with struggle and energy, death with deadly perfection. The lamp of memory: The guidance provided by the time before machinery ruled. The lamp of obedience: Obedience to the example set by a master's practice rather than by his particular works; otherwise put, strive to be like Stradivari but do not seek to copy his particular violins. Richard Sennett, The Craftsman 125 Best Architecture Books