Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Controlled environments “Controlled environments” are another of modernism’s great obsessions. Extravagant amounts of energy are spent to keep buildings—as well as skyway systems, shopping malls, and domed stadia—at a constant temperature year-round via entirely mechanical means. The folly is not simply a touchy-feely isolation from the authenticities of nature, which can admittedly be cruel, but a larger disciplinary presumption that seeks to extend the centralized authority (central air, central government) of power ever more comprehensively. It is possible that this particular hubris may have pushed Gaia to the tipping point. Michael Sorkin, 20 Minutes in Manhattan At a uniformly comfortable termperatureFascination with control sustainabilitycontrol