Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Chapel of St. Ignatius, Seattle, 1995–7 The exterior walls of the Chapel of St. Ignatius are made of large, complexly interlocking concrete slabs, a variegated golden-brown in color, and the roofs are clad in light grey metal. At the corners where the joints between the wall panels interlock are windows of various rectangular shapes and sizes, and the egg-shaped metal anchors that were used to lift the walls in place project slightly forward, casting small shadows. Robert McCarter & Juhani Pallasmaa, Understanding Architecture Bells ornament