Why Most Published Research Findings Are False A Research Paper by John P.A. Ioannidis journals.plos.org There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance. researchsciencetruth
Both practical and aesthetic concerns The group [of Irwin, Howard, and Wortz]'s thinking here seems to have been influenced to a degree by Christopher Alexander's landmark article, "A City is Not a Tree" (1965)... Irwin referred specifically to Alexander's argument in his effort to sort out his own thinking about how the Miami International Airport might be designed with both practical and aesthetic concerns in mind, allowing for their overlap and emergence from the conditions on the ground. Matthew Simms, Robert Irwin: A Conditional Art A City Is Not a Tree